the rear mounts are different f150 and f250 use the center cross memeber under the cab to bolt down f350 cab has its own cab mounts on the outside of the frame you can make new hole in the cab floor to line them up not a big deal the wiring will be a little different in the cab but you can move the harness over doesnt take long if you pay attention while you work i switched mine out in a day and started putting the dog house back on the next day
